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A key biomarker in remote GLP-1 medication management

GLP-1 agonists are remarkably effective in helping patients lose weight. But this can’t be done in a vacuum. “Ensuring safety and appropriate rate of weight loss is always a concern among healthcare providers who are remotely monitoring patients on GLP1 medication. Without having patients come into a physical clinic, there hasn’t been a means of checking health metrics, such as weight and blood pressure, in a way that they can be easily transferred into their electronic medical record for trending over time” said Kristin Baier, MD VP, Clinical Development at Calibrate, the leading clinician-guided and value-based obesity treatment program. Highlighting the importance of GLP-1 remote patient monitoring regarding weight management. 

 

One data point that’s often overlooked in a patient’s journey on GLP-1s is body composition — the proportion of lean mass and fat mass within the body, which can be subdivided into muscle mass, fat mass, water percentage, and bone mass. We now know this data is more telling than Body Mass Index (BMI). In fact, research has shown that BMI is a poor indicator of overall health and does not take into consideration the difference between muscle and fat mass. BMI oversimplifies health assessments, neglecting insight into crucial factors that measuring body composition can provide. (Science Behind Body Composition, A Withings Study)

 

“When patients lose weight, they are losing a combination of adipose (fat) tissue and lean body mass, which includes skeletal muscle mass, organ density and bone density. Ideally, we want patients to lose adipose tissue and preserve their lean body mass,” continued Kristin Baier, MD. Monitoring body composition over time is crucial, as changes and trends can provide valuable insights into a patient's health status — often more so than individual measurements.

Preventing muscle loss

One known side effect of GLP-1 medications is the loss of muscle mass along with body fat. If care teams only monitor patient progress using a standard scale, they won’t know if their patients are losing too much muscle mass too quickly. Some patients receive a one-time measurement of their body composition during their doctors’ office visit to determine if they’re eligible for a GLP-1 and sometimes during their annual checkup, so care teams are only seeing the data at the beginning and end of the patient journey. Other patients undergo treatment without any assessment of their body composition. By neglecting to measure aspects such as muscle mass, fat distribution, and hydration levels, healthcare providers may overlook crucial indicators that could impact treatment efficacy and patient well-being.

 

Muscle is important for burning calories and maintaining a healthy metabolism, which helps with long-term weight loss success. Loss of muscle mass is associated with an increased risk for lower bone density, fatigue, injuries, decreased strength, and more frequent hospitalizations. Preserving muscle is necessary not just to ensure ongoing physical movement but to protect against cancer, cardiovascular disease, and pulmonary disease. This can be tracked by using a GLP-1 remote patient monitoring to support the patient's journey.   

 

“By measuring body composition, we can accurately determine if this is, in fact, occurring. If we see that pounds are going down but their body fat percentage is staying the same and their muscle mass is decreasing, we can modify lifestyle components such as their type and frequency of exercise and food intake, for instance” shared Kristin Baier, MD.

Combatting GLP-1 agonist plateau

Although GLP-1 agonists tend to spark significant weight loss, most patients eventually reach a plateau in their weight and other metabolic markers like blood pressure. Focusing solely on weight or BMI can sometimes lead to short-term thinking and unsustainable weight loss strategies.

 

By helping patients focus less on specific weight numbers and more on changes in their body composition data, care teams can promote a more holistic approach that supports sustainable weight loss. 

For example, if a patient’s body weight increases or remains stable during treatment, GLP-1 remote patient monitoring and body composition monitoring may reveal that their body fat percentage has decreased while their muscle mass has increased. Although the individual is gaining weight in this scenario, it’s attributed to the growth of muscle tissue rather than an increase in body fat. This type of weight gain, known as lean mass gain, is generally considered positive for overall health and fitness as it can improve strength and metabolic rate.

Moving Forward

In a March 2024 survey conducted by Withings, patients taking GLP-1 medication were asked about the biomarkers they’ve been monitoring throughout their health journey. Among respondents, 37% highlighted body composition as a crucial metric they actively tracked using their Withings devices during their treatment regimen.

 

Write-in responses highlighted the value of regular body composition tracking in supporting healthy habits and addressing concerns about muscle loss.

"[My Withings scale] encouraged daily weigh-ins, identification of more clear lean body mass decrease, [and] increased focus on protein intake and resistance exercise per HCP guidance.” "I watch my muscle mass through the Withings scale. I don’t need my weight to decrease quickly, but I do want to keep or gain muscle.” "I was fearful that I would lose muscle, and the scale helped me to monitor.” "Daily reminder of weight, body composition, and BP (blood pressure) reinforced healthy eating and exercise goals."

Withings Body Pro 2 is an advanced body composition scale that accurately and reliably collects advanced patient biomarkers from the at-home setting and sends them directly to care teams via cellular connectivity.

 

Daily body composition analysis allows for a more personalized approach to treatment. Measuring patients’ body composition while on a GLP-1 therapy is important for assessing treatment effectiveness, monitoring metabolic health, preserving lean body mass, and ensuring overall health and safety for individuals undergoing this type of treatment.

Part 3: Discover the importance of remote monitoring devices after medication ends

Keep Reading [post_title] => Part 2: Supporting Safe and Sustainable Weight Loss With GLP-1s - Why body composition matters [post_excerpt] => GLP-1 agonists are remarkably effective in helping patients lose weight. But this can’t be done in a vacuum. One data point that’s often overlooked in a patient’s journey on GLP-1s is body composition. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => part-2-supporting-safe-and-sustainable-weight-loss-with-glp-1s-part-2-why-body-composition-matters [to_ping] => [pinged] => [post_modified] => 2024-06-27 09:56:59 [post_modified_gmt] => 2024-06-27 09:56:59 [post_content_filtered] => [post_parent] => 0 [guid] => https://withingshealthsolutions.com/?p=1150 [menu_order] => 0 [post_type] => post [post_mime_type] => [comment_count] => 0 [filter] => raw ) [1] => WP_Post Object ( [ID] => 1153 [post_author] => 1 [post_date] => 2024-04-01 06:30:20 [post_date_gmt] => 2024-04-01 06:30:20 [post_content] =>

Strategies for long-term success and patient engagement

Weight gain is likely when patients stop taking a GLP-1 therapy. A 2022 study found patients who took the GLP-1 semaglutide had regained two thirds of their prior weight and had similar cardiometabolic changes a year after stopping the medication. These medications are typically not intended for lifelong use, so care teams should help patients build a routine from the start of their journey to maintain weight loss after medication. Some patients may stop the medication early due to a prescriber recommendation, severe side effects, or the cost or inconvenience of receiving weekly injections. This is why GLP 1 remote patient monitoring  is essential for the success of the program.

 

Prescribers at doctor’s offices and virtual weight loss programs should track patients throughout their journey and when they stop taking GLP-1s. The monitoring of daily progress provides long-term oversight of weight loss goals and maintenance.  

 

“Regular communication and motivation are crucial to helping patients stay on track. The health data Withings devices can capture on a regular basis has helped our Care Teams better monitor patient progress and provide personalized care,” said Lauren Lemieux, MD, FACP, Dipl. ABOM at FORM.

Withings’ newest cellular body composition scale introduces Health Nudges, a first-ever patient engagement feature that delivers messages from a patient’s care team to the screen of their scale. Health Nudges keeps patients engaged by highlighting milestones and sharing health reminders. For example, patients may receive kudos when they reach a particular goal or as an encouragement to keep going on their health journey. 

Avoid weight cycling

Only about one third of people can safely come off GLP-1 without gaining the weight back. Many people who struggle with their weight are familiar with the yo-yo experience of repeatedly losing weight and gaining it back. This is a risk when starting and stopping GLP-1 agonists. 

 

Weight cycling isn’t just tough on a patient’s psyche. Medical experts have found it’s bad for your health. A study published in the Journal of Clinical Endocrinology & Metabolism found that continual fluctuations in weight can strain the cardiometabolic system. That’s why care teams need GLP 1 remote patient monitoring and access to long-term patient health data — so they can recognize patterns and make necessary early interventions.

Tracking for added protection

GLP-1 agonists are still relatively new — the first medications were FDA approved in 2005. Although they are approved for people diagnosed with obesity, an increasing number of medical centers are prescribing them off-label for weight loss. Some physicians caution that there isn’t enough data to know if this is safe. By closely tracking body composition, care teams can gain valuable insights into how the medications are affecting patients on a daily basis.

 

Additionally, daily tracking of metrics such as weight trends, blood pressure, and sleep patterns is now possible through Withings’ full suite of at-home devices. This clinically validated data provides invaluable clues about patients’ health challenges, which can power care teams’ decisions over time. 

Setting patients up for long-term success

Patients who use medication as a quick fix and don't establish healthy habits are likely to regain the weight. It’s crucial to have a day-to-day perspective on the effects of drug and health habits on a patient’s body, for many reasons:

• Demonstrating the medication's efficacy
• Protecting patients from side effects like muscle loss
• Keeping patients engaged in their health journey

Ultimately, having regular insight into a patient’s progress and struggles helps care teams support them — and this gives them the best chance of long-term success. 

Interested in partnering with us?

Contact Us [post_title] => Part 3: Supporting Safe and Sustainable Weight Loss With GLP-1s - Managing weight after medication [post_excerpt] => Weight gain is likely when patients stop taking a GLP-1 therapy. A 2022 study found patients who took the GLP-1 semaglutide had regained two thirds of their prior weight and had similar cardiometabolic changes a year after stopping the medication. Prescribers at doctor’s offices and virtual weight loss programs should track patients throughout their journey and when they stop taking GLP-1s. This monitoring of daily progress provides long-term oversight of weight loss goals and maintenance. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => part-3-supporting-safe-and-sustainable-weight-loss-with-glp-1s-managing-weight-after-medication [to_ping] => [pinged] => [post_modified] => 2024-06-27 12:48:36 [post_modified_gmt] => 2024-06-27 12:48:36 [post_content_filtered] => [post_parent] => 0 [guid] => https://withingshealthsolutions.com/?p=1153 [menu_order] => 0 [post_type] => post [post_mime_type] => [comment_count] => 0 [filter] => raw ) [2] => WP_Post Object ( [ID] => 1029 [post_author] => 1 [post_date] => 2024-02-01 07:15:00 [post_date_gmt] => 2024-02-01 07:15:00 [post_content] =>

SUMMARY

This case study explores how a virtual medical weight loss practice integrated a cellular remote patient monitoring scale into their program, improving the patient onboarding experience and reducing operational needs. 

Partner

FORM

Challenge

Needed a reliable and efficient weight tracking solutions that seamlessly integrated with existing workflow

Solution

Withings Body Pro Scale

Results

Reduced time spend technical troubleshooting and manual scale ordering needs by 20%

“Reducing support time is the biggest impact of partnering with Withings. Thanks to the quality of the Withings scale and level of partner support we don’t need additional staff to troubleshoot and support scale issues for our patients."

Derek Rowley, VP of Operations at FORM

BACKGROUND

FORM is a virtual medical weight loss practice that helps patients with obesity achieve their weight loss and health goals by combining evidence-based clinical care with cutting-edge technology. FORM patients work 1:1 with a dedicated physician and Registered Dietitian who provide a personalized weight loss plan that addresses nutrition, physical activity, and mindset shifts, along with a prescription for FDA-approved medication including GLP-1s, when appropriate. FORM provides all care virtually through its app where patients connect with their Care Team through video visits and messaging and access tools such as food journaling and weight tracking, along with educational resources, improving the patient onboarding and care. 

 

As part of their remote patient monitoring program which is billed through insurance, FORM patients are required to provide weight readings throughout the month. As a result, a scale is provided as part of their onboarding process. It is important that the scale is accurate and reliable to collect readings, as well as easy to use and engaging, so patients comply with the weight reading requirement.

CHALLENGE

FORM faced a challenge when they added remote patient monitoring as an offering given they needed to receive weight readings a minimum of 16 days each month to bill with specific CPT codes. They needed to make providing the weight readings easy for patients and looked for a scale vendor capable of digitally transmitting patient weight values, replacing their prior manual process where a patient sent a picture of the scale reading or typed in their value. Therefore, they required a reliable and efficient weight tracking solution that seamlessly integrated with their platform and existing workflow, for improving the patient onboarding.

 

FORM initially partnered with a cellular scale vendor and experienced a number of logistical and support challenges. The process of ordering scales was manual and tedious for their operations team and they experienced delayed shipments and inventory shortages. The vendor did not offer a dropship solution that could automate logistics and improve operational efficiency.

 

The logistical issues impacted the onboarding experience for FORM patients who often experienced long wait times for the scale to arrive, which meant their first visit with a FORM clinician could be delayed. Once they received the scale, some patients encountered connectivity issues and calibration challenges. When these technical issues arose, response time from the vendor was slow. It could take days for the FORM operations team to get troubleshooting tips from the prior vendor’s support team.

SOLUTION

FORM partnered with Withings Health Solutions to improve the FORM patient experience by including a high quality scale, automating logistics, and providing world-class scale support. 

 

With Withings Body Pro, FORM patients receive a trusted and brand-name cellular scale that is synonymous with high quality, ease of use, and reliability. The Withings scale enhances the FORM patient experience from onboarding and throughout the program.

 

A significant game-changer for the FORM operations team was integrating Withings' dropshipping capability, which eliminated inventory management responsibility for the FORM team, and streamlined logistics and the onboarding process. With Withings dropshipping capabilities, ordering a scale became as simple as the click of a button and the scale is delivered to patients within days.

"With Withings dropshipping, we've streamlined our scale shipments, making it incredibly easy for patients to start their program right away. We have confidence that the scale will arrive promptly and function reliably. We don’t want to have to think about inventory management and fulfillment - that’s not our game. Thanks to Withings' dropshipping capability, we can focus on other critical pieces of our onboarding experience."

Derek Rowley, VP of Operations at FORM.

FORM also integrated the Withings API into their specific workflow to ensure that when the patient steps on the scale their weight measurement flows directly to the FORM app, so that patients do not have to manually provide weight values, improving the patient onboarding. The scale’s body positioning feature helps patients know how to shift their body to get an accurate reading. Withings Body Pro scale has the ability to store readings offline and transmit the data once a connection is established, ensuring that no weight readings are ever lost due to connectivity issues, and making the patient data tracking more reliable and consistently transmitted to the FORM Care Team to act on.

RESULTS

The partnership between FORM and Withings Health Solution significantly enhanced their operational efficiency. The reduced time spent on troubleshooting technical issues and manual scale ordering opened up to 20% of their Enrollment Specialists’ time to focus on more value-added tasks. The once cumbersome process of scale troubleshooting has been reduced to no more than a couple of hours total a week.

 

With Withings dropshipping API integration, FORM patients receive their scale in a matter of days and can begin tracking their weight before their first appointment with their FORM clinician. This gets them in the habit of tracking their weight and, most importantly, allows them to start the program right away instead of experiencing delays after signing up. FORM clinicians receive the patient’s baseline weight data before their initial meeting which facilitates personalized treatment plans. The Withings dropshipping solution enables FORM to avoid the higher costs and inventory management risks that can exist when using a third-party fulfillment center or doing it themselves.

 

Higher reliability and consistency in data transmission was another major outcome in the partnership between FORM and Withings Health Solutions. “Overall our weight readings are more accurate and we receive them more consistently since we've partnered with Withings," said Jason Drapinski, Enrollment Specialist at FORM. With more consistent and reliable data transmission, FORM Care Teams can trust the data they receive, allowing for more accurate patient assessments, an improved patient onboarding experience and improved health outcomes.

20%

reduction in time spent troubleshooting technical issues and manual scale ordering 

Interested in partnering with us?

Contact Us

BACKGROUND

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A key biomarker in remote GLP-1 medication management

GLP-1 agonists are remarkably effective in helping patients lose weight. But this can’t be done in a vacuum. “Ensuring safety and appropriate rate of weight loss is always a concern among healthcare providers who are remotely monitoring patients on GLP1 medication. Without having patients come into a physical clinic, there hasn’t been a means of checking health metrics, such as weight and blood pressure, in a way that they can be easily transferred into their electronic medical record for trending over time” said Kristin Baier, MD VP, Clinical Development at Calibrate, the leading clinician-guided and value-based obesity treatment program. Highlighting the importance of GLP-1 remote patient monitoring regarding weight management. 

 

One data point that’s often overlooked in a patient’s journey on GLP-1s is body composition — the proportion of lean mass and fat mass within the body, which can be subdivided into muscle mass, fat mass, water percentage, and bone mass. We now know this data is more telling than Body Mass Index (BMI). In fact, research has shown that BMI is a poor indicator of overall health and does not take into consideration the difference between muscle and fat mass. BMI oversimplifies health assessments, neglecting insight into crucial factors that measuring body composition can provide. (Science Behind Body Composition, A Withings Study)

 

“When patients lose weight, they are losing a combination of adipose (fat) tissue and lean body mass, which includes skeletal muscle mass, organ density and bone density. Ideally, we want patients to lose adipose tissue and preserve their lean body mass,” continued Kristin Baier, MD. Monitoring body composition over time is crucial, as changes and trends can provide valuable insights into a patient's health status — often more so than individual measurements.

Preventing muscle loss

One known side effect of GLP-1 medications is the loss of muscle mass along with body fat. If care teams only monitor patient progress using a standard scale, they won’t know if their patients are losing too much muscle mass too quickly. Some patients receive a one-time measurement of their body composition during their doctors’ office visit to determine if they’re eligible for a GLP-1 and sometimes during their annual checkup, so care teams are only seeing the data at the beginning and end of the patient journey. Other patients undergo treatment without any assessment of their body composition. By neglecting to measure aspects such as muscle mass, fat distribution, and hydration levels, healthcare providers may overlook crucial indicators that could impact treatment efficacy and patient well-being.

 

Muscle is important for burning calories and maintaining a healthy metabolism, which helps with long-term weight loss success. Loss of muscle mass is associated with an increased risk for lower bone density, fatigue, injuries, decreased strength, and more frequent hospitalizations. Preserving muscle is necessary not just to ensure ongoing physical movement but to protect against cancer, cardiovascular disease, and pulmonary disease. This can be tracked by using a GLP-1 remote patient monitoring to support the patient's journey.   

 

“By measuring body composition, we can accurately determine if this is, in fact, occurring. If we see that pounds are going down but their body fat percentage is staying the same and their muscle mass is decreasing, we can modify lifestyle components such as their type and frequency of exercise and food intake, for instance” shared Kristin Baier, MD.

Combatting GLP-1 agonist plateau

Although GLP-1 agonists tend to spark significant weight loss, most patients eventually reach a plateau in their weight and other metabolic markers like blood pressure. Focusing solely on weight or BMI can sometimes lead to short-term thinking and unsustainable weight loss strategies.

 

By helping patients focus less on specific weight numbers and more on changes in their body composition data, care teams can promote a more holistic approach that supports sustainable weight loss. 

For example, if a patient’s body weight increases or remains stable during treatment, GLP-1 remote patient monitoring and body composition monitoring may reveal that their body fat percentage has decreased while their muscle mass has increased. Although the individual is gaining weight in this scenario, it’s attributed to the growth of muscle tissue rather than an increase in body fat. This type of weight gain, known as lean mass gain, is generally considered positive for overall health and fitness as it can improve strength and metabolic rate.

Moving Forward

In a March 2024 survey conducted by Withings, patients taking GLP-1 medication were asked about the biomarkers they’ve been monitoring throughout their health journey. Among respondents, 37% highlighted body composition as a crucial metric they actively tracked using their Withings devices during their treatment regimen.

 

Write-in responses highlighted the value of regular body composition tracking in supporting healthy habits and addressing concerns about muscle loss.

"[My Withings scale] encouraged daily weigh-ins, identification of more clear lean body mass decrease, [and] increased focus on protein intake and resistance exercise per HCP guidance.” "I watch my muscle mass through the Withings scale. I don’t need my weight to decrease quickly, but I do want to keep or gain muscle.” "I was fearful that I would lose muscle, and the scale helped me to monitor.” "Daily reminder of weight, body composition, and BP (blood pressure) reinforced healthy eating and exercise goals."

Withings Body Pro 2 is an advanced body composition scale that accurately and reliably collects advanced patient biomarkers from the at-home setting and sends them directly to care teams via cellular connectivity.

 

Daily body composition analysis allows for a more personalized approach to treatment. Measuring patients’ body composition while on a GLP-1 therapy is important for assessing treatment effectiveness, monitoring metabolic health, preserving lean body mass, and ensuring overall health and safety for individuals undergoing this type of treatment.

Part 3: Discover the importance of remote monitoring devices after medication ends

Keep Reading [post_title] => Part 2: Supporting Safe and Sustainable Weight Loss With GLP-1s - Why body composition matters [post_excerpt] => GLP-1 agonists are remarkably effective in helping patients lose weight. But this can’t be done in a vacuum. One data point that’s often overlooked in a patient’s journey on GLP-1s is body composition. [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => part-2-supporting-safe-and-sustainable-weight-loss-with-glp-1s-part-2-why-body-composition-matters [to_ping] => [pinged] => [post_modified] => 2024-06-27 09:56:59 [post_modified_gmt] => 2024-06-27 09:56:59 [post_content_filtered] => [post_parent] => 0 [guid] => https://withingshealthsolutions.com/?p=1150 [menu_order] => 0 [post_type] => post [post_mime_type] => [comment_count] => 0 [filter] => raw ) [comment_count] => 0 [current_comment] => -1 [found_posts] => 3 [max_num_pages] => 1 [max_num_comment_pages] => 0 [is_single] => [is_preview] => [is_page] => [is_archive] => [is_date] => [is_year] => [is_month] => [is_day] => [is_time] => [is_author] => [is_category] => [is_tag] => [is_tax] => [is_search] => [is_feed] => [is_comment_feed] => [is_trackback] => [is_home] => 1 [is_privacy_policy] => [is_404] => [is_embed] => [is_paged] => [is_admin] => [is_attachment] => [is_singular] => [is_robots] => [is_favicon] => [is_posts_page] => [is_post_type_archive] => [query_vars_hash:WP_Query:private] => 10bf5761585d95f75359956520d88422 [query_vars_changed:WP_Query:private] => [thumbnails_cached] => [allow_query_attachment_by_filename:protected] => [stopwords:WP_Query:private] => [compat_fields:WP_Query:private] => Array ( [0] => query_vars_hash [1] => query_vars_changed ) [compat_methods:WP_Query:private] => Array ( [0] => init_query_flags [1] => parse_tax_query ) )